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pentobarbital will lessen the level or outcome of ambrisentan by impacting hepatic/intestinal enzyme CYP3A4 metabolism. Minimal/Importance Mysterious.pentobarbital will decrease the extent or result of norgestrel by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Modify Therapy/Monitor Closely. Reasonable CYP3A4 inducers may lessen progestin